— Exosome Shot 2000
— Spicule Booster Serum
— Pore Care
— Smoother Texture
— Radiant-Looking Skin
— Exosome Shot 2000
— Spicule Booster Serum
— Pore Care
— Smoother Texture
— Radiant-Looking Skin
— Exosome Shot 2000
— Spicule Booster Serum
— Pore Care
— Smoother Texture
— Radiant-Looking Skin
— Exosome Shot 2000
— Spicule Booster Serum
— Pore Care
— Smoother Texture
— Radiant-Looking Skin
— Exosome Shot 2000
— Spicule Booster Serum
— Pore Care
— Smoother Texture
— Radiant-Looking Skin
— Exosome Shot 2000
— Spicule Booster Serum
— Pore Care
— Smoother Texture
— Radiant-Looking Skin
— Exosome Shot 2000
— Spicule Booster Serum
— Pore Care
— Smoother Texture
— Radiant-Looking Skin
— Exosome Shot 2000
— Spicule Booster Serum
— Pore Care
— Smoother Texture
— Radiant-Looking Skin
Smooth the Look of Pores in One Tingling Step
For Skin That Feels Textured, Dull, or Congested
When your skin looks uneven, your pores appear more visible, or your makeup sits on texture, your routine may need a targeted booster step.
The Medicube One Day Exosome Shot Pore Serum 2000 is designed to bring that “treatment night” feeling into your skincare routine. The spicule ampoule creates a tingling sensation while helping address the look of pores, dead skin buildup, and rough texture.
Use it at night, follow with a moisturizer, and wake up to skin that looks smoother, fresher, and more refined.
Is This For You?
This set is perfect if you:
- Have visible pores or rough-looking texture
- Want a more intensive K-beauty pore-care step
- Feel like your skin looks dull or uneven
- Want smoother-looking skin before makeup days
- Prefer targeted nighttime treatments
- Are curious about spicule skincare
- Want a serum that feels more active than a basic hydrating product
- Already use toner pads, moisturizers, or pore-care products and want to level up your routine
If your skin looks textured, dull, or less refined than usual, this is the tingling pore-care step your routine may be missing.
See Why Beauty Lovers Are Talking About Exosome Shot
FAQ
Why does this serum tingle?
Why does this serum tingle?
The tingling comes from the spicule-style formula. Medicube explains that the ampoule contains naturally derived micro-particle ingredients that may create a tingling sensation during application.
Is tingling normal?
Is tingling normal?
Yes, mild tingling can be normal with this product. Medicube notes that tingling, redness, itching, and heat sensation may occur and may last for some time. Adjust the amount and frequency based on your skin’s sensitivity.
How often should I use Medicube One Day Exosome Shot 2000?
How often should I use Medicube One Day Exosome Shot 2000?
Start slowly, especially if you are new to spicules or active skincare. Use according to your skin’s tolerance and reduce frequency if your skin feels irritated.
Can I use it every day?
Can I use it every day?
Some users may tolerate regular use, but beginners should introduce it gradually. Sensitive skin should patch test first.
Can I use it around my eyes?
Can I use it around my eyes?
No. Medicube recommends avoiding the area near the eyes and lips.
Should I use it in the morning or at night?
Should I use it in the morning or at night?
Nighttime is best, especially for beginners. Sephora’s directions describe using it after evening cleansing, then finishing with moisturizer.
Can I use it with retinol or strong acids?
Can I use it with retinol or strong acids?
Be careful. Because this product already contains exfoliating ingredients and may tingle, avoid combining it with too many strong actives until you know how your skin reacts.
Do I need moisturizer after this?
Do I need moisturizer after this?
Yes. Medicube recommends finishing with a water-based moisturizer or cream after applying the Exosome Shot.
Does it permanently shrink pores?
Does it permanently shrink pores?
No skincare product can permanently erase pores. This serum helps improve the appearance of pores, texture, and skin smoothness with consistent use.
Product description
Ingredients
Ingredients
Water, Dipropylene Glycol, Glycerin, Butylene Glycol, 1,2-Hexanediol, Niacinamide, Sodium Polyacrylate, Ethylhexyl Palmitate, C12-14 Alketh-12, Hydrogenated Polydecene, Hydrolyzed Sponge, Ethylhexylglycerin, Adenosine, Caprylyl/Capryl Glucoside, Disodium EDTA, Panthenol, Lactobacillus Extracellular Vesicles, Campsis Grandiflora Flower Extract, Pueraria Lobata Root Extract, Pinus Palustris Leaf Extract, Oenothera Biennis Flower Extract, Ulmus Davidiana Root Extract, Calcium Silicate, Sodium Silicate, Betaine Salicylate, Citric Acid, Gluconolactone.
Key Ingredients
Key Ingredients
Exosome-Coated Spicule
Medicube describes this as a needle-shaped spicule technology designed to support pore care and healthier-looking skin. This is the ingredient responsible for the unique tingling booster feel.
Lacto Exosome
A patented Medicube ingredient described by the brand as containing active components such as peptides, amino acids, glutathione, and vitamins to support daily skin concerns and natural-looking skin vitality.
AHA + BHA + PHA
A resurfacing acid blend designed to help with dead skin buildup, textured-looking skin, and skin renewal.
Niacinamide
Helps support the skin barrier, hydration, and a more even, radiant-looking complexion. Medicube and Sephora both highlight niacinamide in the formula.
Panthenol
A soothing, moisturizing ingredient that helps the skin feel more comfortable and hydrated after treatment.
Adenosine
Included in the ingredient list and commonly used in Korean skincare for smoother, more cared-for-looking skin.
Features and Specifications
Features and Specifications
Features
30ml Korean pore-care ampoule
2,000ppm exosome care
Micro-sized spicule booster formula
Tingling ampoule texture
Designed for visible pores and uneven texture
Supports smoother-looking skin
Helps improve the look of dullness and roughness
Contains AHA + BHA + PHA
Contains niacinamide and panthenol
Best used as an evening skincare treatment
Can be used on targeted areas or the full face, avoiding eyes and lips
Pairs well with moisturizer after application
Specifications
Product name: Medicube One Day Exosome Shot Pore Serum 2000
Alternative product name: Medicube Exosome Shot Zero 2,000 PPM Spicule Facial Serum
Brand: Medicube
Product type: Pore-care serum / ampoule / skin booster
Size: 30ml / 1.01 fl. oz.
Use for: Face
Skin type listed on Amazon: All, combination, dry, oily, oily acne-prone, sensitive
Main concerns: Visible pores, rough texture, dullness, uneven-looking skin, dead skin buildup
Key ingredients: Exosome-coated spicule, lacto exosome, AHA + BHA + PHA, niacinamide, panthenol
Recommended routine: Evening use after cleansing, before moisturizer
Important note: Tingling may occur
Good To Know
Good To Know
This product may tingle. A tingling sensation is expected with this type of spicule ampoule, but you should adjust the amount and frequency based on your skin’s sensitivity.
Avoid using near the eyes and lips.
Patch test before regular use, especially if you have sensitive, reactive, or delicate skin.
Do not use on broken, irritated, sunburned, or compromised skin.
Start slowly if you are new to spicules, acids, or intensive pore-care products.
Avoid layering with too many strong actives in the same routine until you know how your skin reacts.
Use sunscreen the next morning, especially because the formula includes exfoliating acid ingredients such as AHA, BHA, and PHA.
For external use only. Amazon’s safety information also states that the product is for external use only.