— Exosome Shot 2000

— Spicule Booster Serum

— Pore Care

— Smoother Texture

— Radiant-Looking Skin

— Exosome Shot 2000

— Spicule Booster Serum

— Pore Care

— Smoother Texture

— Radiant-Looking Skin

— Exosome Shot 2000

— Spicule Booster Serum

— Pore Care

— Smoother Texture

— Radiant-Looking Skin

— Exosome Shot 2000

— Spicule Booster Serum

— Pore Care

— Smoother Texture

— Radiant-Looking Skin

— Exosome Shot 2000

— Spicule Booster Serum

— Pore Care

— Smoother Texture

— Radiant-Looking Skin

— Exosome Shot 2000

— Spicule Booster Serum

— Pore Care

— Smoother Texture

— Radiant-Looking Skin

— Exosome Shot 2000

— Spicule Booster Serum

— Pore Care

— Smoother Texture

— Radiant-Looking Skin

— Exosome Shot 2000

— Spicule Booster Serum

— Pore Care

— Smoother Texture

— Radiant-Looking Skin

 (100 Reviews)

MEDICUBE - One Day Exosome Shot Pore Serum 2000

MEDICUBE - One Day Exosome Shot Pore Serum 2000

A tingling Korean pore-care serum designed to refine the look of pores, smooth uneven texture, and boost your glow.

Regular price $23.99
Regular price $23.99 Sale price $28.99
SAVE 17% Sold out

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MEDICUBE - One Day Exosome Shot Pore Serum 2000

MEDICUBE - One Day Exosome Shot Pore Serum 2000

Regular price $23.99
Regular price $23.99 Sale price $28.99
SAVE 17% Sold out

The Medicube One Day Exosome Shot Pore Serum 2000 is a 30ml Korean skincare ampoule designed for pore care, uneven-looking texture, dullness, and smoother-looking skin. Sephora UK describes it as a revitalizing pore-care ampoule enriched with 2,000ppm of exosomes and micro-sized spicule technology, formulated to support smoother-looking skin, moisture balance, brightness, barrier care, and the appearance of pores and wrinkles.

Amazon describes the product as a “spicule facial serum” and highlights Exosome Shot Zero 2,000 PPM, AHA + BHA + PHA, pore care, dead skin cell care, and skin texture care. The listing also notes that it is sold by Medicube & Aprilskin and that 10K+ units were bought in the past month at the time the page was retrieved.

Medicube’s official page highlights key ingredients including exosome-coated spicule, lacto exosome, AHA + BHA + PHA, niacinamide, and panthenol. It also notes that the product can create tingling, redness, itching, or a heat sensation, which may happen due to the naturally derived micro-particle ingredients.

A Tingling Skin Booster for Pores, Texture & Glow

Some skincare feels basic. This feels like a skin reset.

The Medicube One Day Exosome Shot Pore Serum 2000 is designed for people who want a more targeted K-beauty treatment for visible pores, rough texture, dull-looking skin, and uneven-looking tone. Inspired by the principles of microneedling, the formula uses micro-sized, needle-shaped spicules to create a tingling booster effect while supporting smoother, clearer, and more radiant-looking skin.

It is ideal as a nighttime treatment step after cleansing and before moisturizer. Use it when your skin looks rough, tired, congested, or less refined than usual.

Standard evening routine

After cleansing, apply a small amount to the face as the first step of your skincare routine.

Avoid the eye area and lips.

Gently massage and press into the skin to help absorption.

Follow with a water-based moisturizer or a calming cream.

Use at night, especially if your skin is new to spicule or exfoliating treatments.

Beginner routine

Cleanse your skin.

Prep with a gentle toner pad or hydrating toner.

Apply the Exosome Shot only to targeted areas, such as visible pores or uneven texture.

Finish with moisturizer.

Suggested routine order

Cleanser

Hydrating toner or toner pad

Medicube One Day Exosome Shot Pore Serum 2000

Soothing serum, optional

Water-based moisturizer

SPF the next morning

Medicube’s official instructions recommend applying it after cleansing, avoiding the eyes and lips, then finishing with a moisturizer. The brand also recommends patch testing for sensitive or delicate skin.

All orders are processed promptly and shipped with tracking to ensure a safe and reliable delivery. Once shipped, you will receive tracking details to follow your order until it arrives.

Glow Hana offers a satisfaction guarantee, allowing you to try the product with confidence. If you are not satisfied, our support team is available to assist you.

View full details

Smooth the Look of Pores in One Tingling Step

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Refines the Look of Pores

Designed for areas where pores look enlarged, congested, or more visible than usual.

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Smooths Uneven Texture

Helps skin look more polished, refined, and makeup-ready with consistent use.

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Boosts Radiance

Targets dull-looking skin and helps support a fresher, more energized glow.

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Strengthens Your Routine

A more intensive treatment step for nights when your skin needs more than a basic serum.

 
 

For Skin That Feels Textured, Dull, or Congested

When your skin looks uneven, your pores appear more visible, or your makeup sits on texture, your routine may need a targeted booster step.

The Medicube One Day Exosome Shot Pore Serum 2000 is designed to bring that “treatment night” feeling into your skincare routine. The spicule ampoule creates a tingling sensation while helping address the look of pores, dead skin buildup, and rough texture.

Use it at night, follow with a moisturizer, and wake up to skin that looks smoother, fresher, and more refined.

 
 

Is This For You?

This set is perfect if you:

  • Have visible pores or rough-looking texture
  • Want a more intensive K-beauty pore-care step
  • Feel like your skin looks dull or uneven
  • Want smoother-looking skin before makeup days
  • Prefer targeted nighttime treatments
  • Are curious about spicule skincare
  • Want a serum that feels more active than a basic hydrating product
  • Already use toner pads, moisturizers, or pore-care products and want to level up your routine

    If your skin looks textured, dull, or less refined than usual, this is the tingling pore-care step your routine may be missing.

  • Amazing Results in Just One Week! My Skin Has Never Looked Better!

    Tania

  • I was nervous to try, but it's so mild!

    I was nervous to try this because of the spicules, since I’ve never used a spicule based product before. I chose the 2000 PPM Exosome Shot to start on the gentler side, and I was pleasantly surprised by how mild it actually feels on the skin. I use this once a week after cleansing (about two pumps), gently pat it in, and then follow with my nighttime moisturizer. There is a very slight pokey sensation on application, but it’s not painful or irritating- just noticeable enough to know it’s there. By morning, my skin looks noticeably smoother, more refined, and almost glass-like.

    Jamie

  • Good skin penetration.

    This works well at leaving smooth skin. Stings a little but tolerable. If you have active irritation I wouldn’t use it because it will burn bad. But once you’re healed it’s a good option. It’s not stick and doesn’t have a scent. My skin feels good after use. It helps with hydration and better product absorption.

    Emilly J

  • Revitalize Your Skin with a Boost of Confidence

    I've tried a fair share of serums in my quest for smooth, even skin, but this liquid skin booster is a standout. It’s like a mini-facial in a bottle, designed to breathe new life into tired, uneven skin. The moment I started using it, I noticed an improvement in my skin texture and tone, especially around those pesky pores that always seem to hog the spotlight. The micro-sized, needle-like design is a fascinating touch, ensuring that the active ingredients dive right into my skin where they're needed most.

    Carly

     
     
    REFINE. SMOOTH. GLOW — ONE TINGLING STEP AT A TIME
     
     
     
     

    FAQ

    The tingling comes from the spicule-style formula. Medicube explains that the ampoule contains naturally derived micro-particle ingredients that may create a tingling sensation during application.

    Yes, mild tingling can be normal with this product. Medicube notes that tingling, redness, itching, and heat sensation may occur and may last for some time. Adjust the amount and frequency based on your skin’s sensitivity.

    Start slowly, especially if you are new to spicules or active skincare. Use according to your skin’s tolerance and reduce frequency if your skin feels irritated.

    Some users may tolerate regular use, but beginners should introduce it gradually. Sensitive skin should patch test first.

    No. Medicube recommends avoiding the area near the eyes and lips.

    Nighttime is best, especially for beginners. Sephora’s directions describe using it after evening cleansing, then finishing with moisturizer.

    Be careful. Because this product already contains exfoliating ingredients and may tingle, avoid combining it with too many strong actives until you know how your skin reacts.

    Yes. Medicube recommends finishing with a water-based moisturizer or cream after applying the Exosome Shot.

    No skincare product can permanently erase pores. This serum helps improve the appearance of pores, texture, and skin smoothness with consistent use.

     
     

    Product description

    Water, Dipropylene Glycol, Glycerin, Butylene Glycol, 1,2-Hexanediol, Niacinamide, Sodium Polyacrylate, Ethylhexyl Palmitate, C12-14 Alketh-12, Hydrogenated Polydecene, Hydrolyzed Sponge, Ethylhexylglycerin, Adenosine, Caprylyl/Capryl Glucoside, Disodium EDTA, Panthenol, Lactobacillus Extracellular Vesicles, Campsis Grandiflora Flower Extract, Pueraria Lobata Root Extract, Pinus Palustris Leaf Extract, Oenothera Biennis Flower Extract, Ulmus Davidiana Root Extract, Calcium Silicate, Sodium Silicate, Betaine Salicylate, Citric Acid, Gluconolactone.

    Exosome-Coated Spicule

    Medicube describes this as a needle-shaped spicule technology designed to support pore care and healthier-looking skin. This is the ingredient responsible for the unique tingling booster feel.

    Lacto Exosome

    A patented Medicube ingredient described by the brand as containing active components such as peptides, amino acids, glutathione, and vitamins to support daily skin concerns and natural-looking skin vitality.

    AHA + BHA + PHA

    A resurfacing acid blend designed to help with dead skin buildup, textured-looking skin, and skin renewal.

    Niacinamide

    Helps support the skin barrier, hydration, and a more even, radiant-looking complexion. Medicube and Sephora both highlight niacinamide in the formula.

    Panthenol

    A soothing, moisturizing ingredient that helps the skin feel more comfortable and hydrated after treatment.

    Adenosine

    Included in the ingredient list and commonly used in Korean skincare for smoother, more cared-for-looking skin.

    Features

    30ml Korean pore-care ampoule

    2,000ppm exosome care

    Micro-sized spicule booster formula

    Tingling ampoule texture

    Designed for visible pores and uneven texture

    Supports smoother-looking skin

    Helps improve the look of dullness and roughness

    Contains AHA + BHA + PHA

    Contains niacinamide and panthenol

    Best used as an evening skincare treatment

    Can be used on targeted areas or the full face, avoiding eyes and lips

    Pairs well with moisturizer after application

    Specifications

    Product name: Medicube One Day Exosome Shot Pore Serum 2000

    Alternative product name: Medicube Exosome Shot Zero 2,000 PPM Spicule Facial Serum

    Brand: Medicube

    Product type: Pore-care serum / ampoule / skin booster

    Size: 30ml / 1.01 fl. oz.

    Use for: Face

    Skin type listed on Amazon: All, combination, dry, oily, oily acne-prone, sensitive

    Main concerns: Visible pores, rough texture, dullness, uneven-looking skin, dead skin buildup

    Key ingredients: Exosome-coated spicule, lacto exosome, AHA + BHA + PHA, niacinamide, panthenol

    Recommended routine: Evening use after cleansing, before moisturizer

    Important note: Tingling may occur

    This product may tingle. A tingling sensation is expected with this type of spicule ampoule, but you should adjust the amount and frequency based on your skin’s sensitivity.

    Avoid using near the eyes and lips.

    Patch test before regular use, especially if you have sensitive, reactive, or delicate skin.

    Do not use on broken, irritated, sunburned, or compromised skin.

    Start slowly if you are new to spicules, acids, or intensive pore-care products.

    Avoid layering with too many strong actives in the same routine until you know how your skin reacts.

    Use sunscreen the next morning, especially because the formula includes exfoliating acid ingredients such as AHA, BHA, and PHA.

    For external use only. Amazon’s safety information also states that the product is for external use only.